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Deoxyribonucleic acid, or DNA as we all know it, is a remarkable molecule that holds our genetic information. This genetic information carries the blueprint for an organism's development, its characteristics, and is the basis of inheritance - ever wondered why children share similar features to their parents? It is because of DNA!
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Sign up for freeGenetic variation can be measured by comparing the differences in
Biodiversity can be quantified using species richness.
The genetic molecule is made of ________.
DNA is found in ________.
DNA is found in the nucleus as _______.
The DNA found in mitochondria and chloroplast is similar to those found in bacterial cells.
The process of producing RNA based on DNA base sequences is called _______.
The process of producing polypeptides based on mRNA base sequences is called _________.
Bacterial cells have extrachromosomal DNA.
The extrachromosomal DNA in prokaryotes are called _______.
Bacterial cells can transfer their plasmids to other bacterial cells via ________.
Genetic variation can be measured by comparing the differences in
Biodiversity can be quantified using species richness.
The genetic molecule is made of ________.
DNA is found in ________.
DNA is found in the nucleus as _______.
The DNA found in mitochondria and chloroplast is similar to those found in bacterial cells.
The process of producing RNA based on DNA base sequences is called _______.
The process of producing polypeptides based on mRNA base sequences is called _________.
Bacterial cells have extrachromosomal DNA.
The extrachromosomal DNA in prokaryotes are called _______.
Bacterial cells can transfer their plasmids to other bacterial cells via ________.
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Team Genetic Information Teachers
You can find DNA primarily in the nucleus as chromosomes, as DNA is an extremely long molecule. DNA is also found in the mitochondria and chloroplast of plants in the form of circular DNA. To make it easier to analyse DNA, we refer to short sections of DNA as genes and different versions of the same genes as alleles. It is the base sequence of these genes that we are interested in as it determines the amino acid sequence of proteins, as illustrated below in the diagram.
Base sequence of DNA and amino acid sequence of proteins
The genetic information stored in the base sequence of genes is transferred through protein synthesis. This process requires transcription and translation and requires other molecules like RNA to be present.
This process of transferring genetic information is a little different in prokaryotic cells. Prokaryotic cells, such as bacteria, carry their genes in extrachromosomal DNA called plasmids. These are circular pieces of DNA that are transferred to other bacteria through processes called conjugation and transformation.
In the previous section, we discussed that DNA enables offspring to share similar features to their parents. So why then do children also have different features from their parents? This is where genetic variation comes in, and this describes the differences in DNA between individuals.
Genetic variation explains the differences between individuals in a species caused by changes in the DNA. The main causes of this phenomenon are mutations, meiosis and random fertilisation.
Mutations describe the changes to the base sequence of genes. Below, you will see an example of a section of mutated DNA. This has the ability to change an organism's characteristics; for example, a mutation in the gene coding for a moth's wing colour can turn the original brown to a darker black colour. Mutations can have a disadvantageous effect, an advantageous effect or no effect on an organism. When the allele is advantageous, the organism has an increased chance of survival and a phenomenon called natural selection occurs. We'll take a look at this in the next section.
Original and mutated DNA sequence
Meiosis and sexual reproduction also introduce genetic variation into a population. Meiosis, a type of cell division, involves processes called crossing over and independent assortment. These describe the exchange of DNA between chromosomes and their alignment in the cell, both of which result in changes to the DNA.
All male sperm and female eggs (gametes) contain slightly different DNA (due to meiosis), and the fertilisation between these gametes is a completely random process. This is great for genetic variation because it means the resulting offspring will also have its own unique set of DNA.
Natural selection describes the process whereby organisms that possess characteristics that improve their ability to survive will live on to reproduce. These characteristics are granted primarily through genetic mutations, which give these organisms advantageous alleles. For example, moths with a genetic mutation that grants them a darker wing colour can camouflage from their prey and survive better than moths with a lighter wing colour.
Predation is termed selection pressure as it is a factor that affects the chances of an organism's survival. Availability of food and shelter are also selection pressures that drive natural selection.
Differences between individuals are not only caused by DNA changes. Environmental factors can also modify the characteristics of an organism. Different environments will have different living conditions.
For example, plants that are exposed to more sunlight have a better chance of growing larger than plants that are in the shade for most of the day.
Genetic variation and environmental variation intersect, and they both play a role in the resulting characteristics of an organism, also called the phenotype. Therefore, it is the combination of these factors which explains the variation in individuals.
The genetic variation found within a species can be quantified by:
Comparing the differences in the base sequence of DNA
Comparing the differences in the amino acid sequence of proteins
To do this, we have to extract DNA or proteins, which are then analysed.
Biodiversity describes the variation of species we see within a community. This can be quantified using species richness. Species richness measures the number of different species in a community, for example, the number of different species found in a waterfall. Another form of measurement is the index of diversity, a formula that describes the relationship between the number of different species in a community (species richness) to the number of organisms in each species (species evenness).
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What are the sources of genetic variation?
Genetic variation is caused by mutations, meiosis and random fertilisation. Mutations are changes in the base sequence of DNA. Meiosis involves a process called crossing over, which describes the exchange of DNA between parental chromosomes. Meiosis also involves independent assortment, which is the random alignment of chromosomes in a cell before division. Fertilisation between sperm and an egg is also a random process, and this causes genetic variation as each gametic cell contains a unique set of DNA.
What is genetic information?
Genetic information describes the DNA base sequence of genes that code for proteins.
How does DNA transfer genetic information?
DNA transfers genetic information during protein synthesis - transcription and translation. Transcription describes the process in which messenger RNA (mRNA) is created from DNA and is delivered to the ribosomes. Translation describes the process in which ribosomes 'read' the genetic code on the mRNA to make a chain of amino acids, resulting in a protein.
Which prokaryotic feature allows the exchange of genetic information?
Prokaryotic cells contain structures called plasmids, which are circular molecules of DNA and can replicate independently. These plasmids can be transferred to other bacteria through conjugation and transformation.
What are the 3 types of genetic variation?
The 3 types of genetic variation include mutations, crossing over and independent segregation.
Mutations describe changes to the DNA base sequence. Crossing over is the exchange of genetic material between homologous chromosomes. Independent segregation involves the random alignment of non-identical chromosomes on the metaphase plate.
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