John Hunter

Though largely criticised during his time for his often unorthodox methods of medical experimentation, John Hunter is now revered as having contributed greatly to modern medicine. Through constantly challenging and pushing the boundaries of medicine through experimentation and investigation during his time, John Hunter earned the prestigious title of the founder of pathological anatomy.

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    John Hunter Biography

    John Hunter was born in 1728 in Lanarkshire, Scotland. Never completing a course of study at any university, Hunter began working as a laboratory assistant in the anatomy school of his older brother William Hunter at the age of 20 in 1748. Hunter spent 11 years studying autonomy in his brother's company and dissecting rooms, and from 1749-1750 he observed surgeon William Cheselden.

    John Hunter Portrait of John Hunter StudySmarterFig. 1 - Portrait of John Hunter

    Hunter went on to study human anatomy extensively and became extremely knowledgeable on the subject. During his studies, Hunter demonstrated a great deal of interest in dissection as well as a great understanding of various types of scientific research.

    Did you know? Hunter went on to qualify as an assistant surgeon in 1756 and as a surgeon in 1768 at St George's hospital.

    William Hunter, John Hunter's older brother, was a well-known medical practitioner and obstetrician. Through this role, John Hunter gained invaluable medical insight. Hunter obtained the skills he needed through his experiences working in his brother William's laboratory. This exposure helped him to understand the importance of scientific investigations and methods within medicine.

    Obstetrician

    A doctor who specialises in medical care for women during pregnancy and the delivery of babies.

    John Hunter Military

    After gaining some basic, but nevertheless formal, training in some aspects of medicine, John Hunter was commissioned in the Seven Years' War (1756-1763) between Britain and France. In this pre-Listerian era, it was difficult, if not impossible, for an aspiring medical student or civilian to gain surgical experience as it pre-dated the discovery of antiseptic. This was one of the main reasons that John Hunter served as an army surgeon; this opportunity meant that he could develop his skills and training, gaining experience along the way.

    Pre-Listerian Era

    This refers to the medical period before Joseph Lister's discovery of antiseptic was introduced into medicine.

    Hunter was able to demonstrate his extensive knowledge of human anatomy in this role. Hunter was commissioned as an army surgeon in Portugal and Belle Isle in France and lived here for three years, putting his skills to good use. Here Hunter acquired "surgical skills on gunshot wounds and inflammation".1

    The experiences he encountered not only allowed him to improve his practical skills but also allowed him to enhance his theoretical knowledge of medicine. For example, when John Hunter arrived in Portugal, the general protocol for treating gunshot wounds was extremely primitive and outdated.

    Gunshot wounds were treated at the time with bloodletting, unnecessary amputations, or extremely invasive and often deadly procedures to remove the bullets.

    A Brief History of Bloodletting

    Bloodletting, which originated in Ancient Egypt, was a medical theory. People generally believed that many illnesses were caused by an imbalance of blood. Due to this, practitioners and surgeons would make small cuts in veins and arteries to release blood.

    Over time, this idea was developed by theorists, including Hippocrates. Hippocrates believed that good health was determined by the balance of the four humours: black bile, yellow bile, phlegm, and blood.

    John Hunter Four Humours Diagram StudySmarterFig. 2 - The theory of the Four Humours was a popular albeit untrue belief about how the human body worked

    In Medieval Europe, this theory quickly became a popular theory of medicine and the treatment of nearly every disease. As such, during wars, people often died of excessive blood loss due to the extremely archaic manner in which gunshot wounds were treated.


    During this era, surgery was a very risky procedure because there was no way to prevent bacterial infection, and anaesthesia had not yet been properly developed.

    Anaesthesia

    Anaesthesia is an artificially induced insensitivity to pain; this is often administrated by gas or injection.

    The moment John Hunter arrived, he cleverly identified that there was an issue with this form of treatment and began using his scientific methodology.

    John Hunter Discovery

    John Hunter observed five French soldiers who had been wounded by gunshots during the war but had not been treated. Despite having sustained gunshot wounds, John Hunter found that the patients were able to heal.

    In this observation, John Hunter made a discovery. Allowing gunshot wounds to heal naturally ultimately resulted in higher survival rates. Hunter, however, still urged that gunshot wounds be properly cleaned to prevent infection from spreading.

    In light of this discovery, John Hunter proposed that surgery should only be performed in rare cases of low-risk gunshot injuries. He concluded that:

    • Gunshot bullets were only to be removed if the wound was superficial and the bullet was easy to remove.
    • Operations were only to be done if the procedure was crucial in restoring a functional anatomical process.

    The discovery was extremely progressive and demonstrated Hunter's focus on scientific methods in his research for the profession of medicine.

    Did you know? Due to the advancements in modern weaponry, this method is practically inapplicable today. Due to these advancements, the risks of internal damage and serious infection have become too high to avoid surgery.

    Hunter died in 1793 from a heart attack. However, his research was published posthumously in 1794, with the paper Treatise of Blood, Inflammation and Gunshot Wounds.

    John Hunter Photograph of Joseph Lister StudySmarterFig. 3 - Photograph of Joseph Lister, the man who developed antiseptic treatments

    Despite being unaware that infections cause inflammation, Hunter made insightful observations in his research about how inflammation is related to smallpox, venereal diseases, and tuberculosis. The observations made by Hunter influenced the later pioneer of antiseptic treatment, Joseph Lister.

    Smallpox

    Contagious disease caused by the variola virus.

    Venereal Diseases

    A disease which is commonly known to be sexually transmitted.

    Tuberculosis

    A bacterial infection spread through inhaling the liquids dispersed from the coughs and sneezes of the infected.

    Contributions of John Hunter

    John Hunter's contributions to medical procedures and practice continued after he left the army in 1763.

    Dentistry

    In his post-military career, John Hunter spent around five years in dentistry. During this time, he made revolutionary contributions. Based on the knowledge he acquired during the five years, Hunter published The Natural History of Human Teeth in 1777.

    The book described how teeth develop from birth, discussed tooth structure, and proposed a method for treating tooth misalignments. This was the first time that scientific classifications like cuspids, bicuspids, molars, and incisors were used.

    Teaching

    Hunter built up a large surgical practice and trained hundreds of other surgeons with his scientific approach to surgery. It is not surprising that so many of the young surgeons he taught went on to become great medical teachers in nineteenth-century Britain and America. Edward Jenner, who discovered the smallpox vaccine, trained with him and became a close friend.

    Did you know?

    Hunter spent at least five years in a partnership with a well-known dentist at the time, James Spence.

    Hunter started his own private lectures on the practice and principles of surgery in the 1770s, which he began after returning to London in 1763 following his time spent as an army surgeon. Hunter's anatomy school and private surgical practice were founded in London in 1764.

    Venereal Disease

    The study of venereal diseases was also advanced by John Hunter. At the time, both gonorrhoea and syphilis were believed to be caused by the same pathogen. Hunter disagreed, arguing they were separate pathogens. To disprove this theory, John Hunter infected himself with gonorrhoea.

    Due to unknowingly infecting himself with both gonorrhoea and syphilis when he thought it was just gonorrhoea, his results were skewed as he concluded that gonorrhoea developed into syphilis. Even though he came to an incorrect conclusion, his initial hypothesis was correct.

    John Hunter Portrait of Edward Jenner StudySmarterFig. 4 - Portrait of Edward Jenner, the man who developed the medical process of vaccination

    Hunter's book On Venereal Disease (1786) was translated into several languages and was widely studied.

    The work had a significant influence on Edward Jenner. John Hunter was said to have pushed his peer Jenner to conduct experimental research and use his findings to develop effective treatments. By building on Hunter's experiments with inoculation, Jenner eventually developed vaccination.

    Vaccination

    A treatment in which immunity against disease is produced.

    Osteoporosis

    Hunter's observations of the human jaw, along with his experiments on animals, led him to a surprising conclusion. Hunter discovered that new bone formed when the old bone was resorbed. It is for this reason that Hunter is credited with making advances in bone studies, orthopaedics, and the treatment of osteoporosis.

    Orthopaedics

    This is the branch of medicine that specialises in muscle-skeletal conditions and illnesses.

    Osteoporosis

    It is a skeletal disorder that is caused by the deterioration of bone tissue.

    John Hunter Achievements

    Among his contributions to orthopaedics, Hunter discovered the method of bone remodelling using his studies on the process of repairing the bone and the regeneration of tendon, cartilage, and bone. Bone remodelling consists of four stages.

    Bone Remodelling

    1. The formation of a hematoma at the break in the bone.
    2. Fibrocartilaginous callus forms.
    3. The formation of a bony callus.
    4. The remodelling and addition of compact bone.

    Hunter studied how fractures would heal in several different types of animals, in particular the ostriches at Earls Court. He observed the replacement of the fracture hematoma by an ossified cartilaginous callus that underwent endosteal remodelling, marrow reformation, and resorption of excess bone.2

    Importance of John Hunter

    Hunter is considered one of the greatest surgeons of all time. John Hunter's advancements during his time were revolutionary, especially his advocacy of scientific research and experimentation as a means to develop treatments.

    • Later revolutionary thinkers like Edward Jenner focused deeply upon building on Jenner's experimentation, which led to the creation of vaccination. Vaccination is considered to be one of the most significant advances in modern medicine.
    • While serving as an army surgeon, John Hunter articulated some extremely important ideas that saved countless lives by avoiding dangerous and unnecessary procedures.
    • John Hunter conducted around 2,000 dissections during his lifetime, which contributed to the understanding of the human body and how to treat it effectively. The significance of Hunter's contributions cannot be understated, as they were in an era before antiseptics and vaccinations.
    • Hunter's dissections, discoveries and treatments aided not only the growth of British hospitals but also their enhancement. His history, education, and drive to develop surgery meant that the role of a surgeon became more informed and restricted to scientists instead of tradesmen.
    • Public Health in Industrial Britain was far from safe. However, John Hunter encouraged other doctors to study the anatomy of both humans and animals to understand how the body works, drastically improving public health and healthcare.
    • Hunter advocated for the lessening of unnecessary and unsafe surgical procedures. This aided in the growth of British hospitals as it allowed them to practice safely and efficiently.

    John Hunter - Key takeaways

    • John Hunter made immense contributions to the field of medicine and is regarded as the founder of pathological anatomy, making impressive contributions to the field of surgery, dentistry, orthopaedics and venereal diseases.
    • John Hunter emphasised the importance of using scientific methodology and experimentation to create effective forms of medical treatment.
    • John Hunter received practical surgical experience after enlisting in the Seven Years' War (1756-63). He served as an army surgeon in 1760 and pioneered the understanding of gunshot wound treatment.
    • Hunter qualified as an assistant surgeon in 1756 and then a surgeon in 1768 at St George's Hospital. Here Hunter pushed individuals such as Edward Jenner to understand the importance of using scientific experimentation to guide medical advancement. This helped Edward Jenner later go on to create vaccinations.
    • Hunter's contributions to the field of surgery also influenced Joseph Lister, who later went on to develop antiseptic treatments.

    References

    1. Yasemin Kaya, (2016). John Hunter (1728–1793) and his legacy to science. Pg.32
    Frequently Asked Questions about John Hunter

    What did John Hunter discover?

    John Hunter discovered many things and made many advancements in medicine, treatment and Public Health in the UK. Some of these included his discovery that gunshot wounds could heal naturally whilst being cleaned to prevent infection. Hunter also made insightful observations about inflammation as it related to smallpox, venereal diseases, and tuberculosis. Hunter also discovered the stages of bone remodelling.

    Who is john hunter?

    John Hunter was a British surgeon in the 18th century. He is also recognised as one of the great contributors to science and surgery. Hunter specialised in dentistry, gunshot wounds, venereal diseases and child development.

    What was John Hunter's major contribution to modern medicine?

    John Hunter's major contribution to modern medicine is this work on dissections, discoveries and treatments. These not only set the foundations that later discovered vaccination, but also helped the growth of British Hospitals safely.

    When did John Hunter discover osteoporosis?

    John Hunter, discovered osteoporosis in the 1800s.  His discovery of bone remodelling contributed to orthopaedics.

    Why was john hunter important?

    John Hunter was important because he helped advance science in its thinking and in its practice. He helped the UK in its understanding of bone growth and remodelling, human teeth, venereal diseases, digestion, child development, the lymphatic system, inflammation and more!

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