Plasma Blood

Blood is the life-giving substance that travels throughout your entire body, delivering oxygen and nutrients to every cell. One critical component of blood, often overlooked, is plasma. You may wonder what exactly is plasma in blood and its significance in the function of your circulatory system.

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StudySmarter Editorial Team

Team Plasma Blood Teachers

  • 9 minutes reading time
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    Understanding Plasma in Blood

    Blood is the life-giving substance that travels throughout your entire body, delivering oxygen and nutrients to every cell. One critical component of blood, often overlooked, is plasma. You may wonder what exactly is plasma in blood and its significance in the function of your circulatory system.

    What is Plasma in Blood – A Detailed Explanation

    Plasma in blood is the liquid element of your blood that holds the blood cells in suspension. It forms about 55% of the body's total blood volume.

    Plasma in blood: It is a straw-colored/yellowish liquid component of blood that makes up about 55% of the body's total blood volume. It is mostly water (up to 95% by volume), and contains dissipated proteins, glucose, clotting factors, mineral ions, hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and blood cells themselves.

    You can think of it as a river through which your cells, hormones, and nutrients can travel across the body. Without it, these crucial elements could not get where they need to go, and your body would not function the way it should.

    Components and Unique Properties of Plasma in Blood

    Blood plasma consists of multiple key components, each carrying out unique functions.

    WaterTransports everything else in the blood
    ProteinsRegulate bodily functions and fight diseases
    SaltsBalance bodily fluids
    HormonesRegulate bodily processes
    GlucoseProvides energy for cells
    Clotting FactorsPrevents excessive bleeding

    Plasma proteins are a group of proteins that float freely in blood plasma. They serve various functions, including as carriers for hormones, vitamins, and enzymes. Albumin, the most abundant plasma protein, helps maintain the body's osmotic balance, that is, it ensures the correct balance between water and dissolved substances in the body's cells.

    Deeper Understanding of Blood Plasma Function

    The functions of plasma in the blood are vast and vital. One primary role is the transportation of substances throughout the body. It carries waste products, ready for excretion from the body, and nutrients, vitamins, and hormones essential for body functions. It also ensures that cells, tissues, and organs receive adequate oxygen to function.

    The clotting factors present in plasma help prevent excessive bleeding when you have a cut or injury. When activated, these proteins interact in a complex sequence of biochemical reactions, forming a clot that blocks blood flow and allows necessary healing to occur.

    Suppose you nick your finger with a kitchen knife while preparing dinner. Pain impulses travel to your brain, signalling the injury. At the physical site of the wound, platelets in your blood start to clump together and work in tandem with plasma proteins to form a clot, stopping blood flow and allowing healing to begin.

    Besides clotting, plasma also plays an integral role in maintaining the body's pH balance, defending against diseases, and regulating body temperature. As such, plasma is essentially the highway of your body, allowing smooth transportation and communication between all your cells.

    Practical Applications of Blood Plasma

    While plasma in blood is undeniably crucial for internal physiological processes, it also has numerous significant external applications. The use of blood plasma extends far beyond our body; it is a vital element in modern medicine, particularly in treating a variety of diseases and medical conditions.

    What is Blood Plasma Used for in the Human Body?

    When utilised within the human body, plasma's primary function is to aid transportation. It carries important substances such as hormones, nutrients, water, salts, and enzymes throughout the body to support various bodily functions.

    Blood plasma is not merely a transporter; it also has certain defensive mechanisms. It carries antibodies, which are vital for warding off infections and diseases. These antibodies are the soldiers of our immune system that target, attack, and neutralise harmful pathogens.

    For instance, if a pathogen, say a bacterium causing pneumonia, enters the body, the immune system produces specific antibodies. These antibodies recognize the bacterium and activate a defensive response, neutralising the bacterium and preventing it from causing harm. It is plasma's job to transport these antibodies to the bacteria's location.

    Key Roles and Therapeutic Implications of Blood Plasma

    Blood plasma plays integral roles in healthcare and medical therapy. For example, it is commonly used in plasma exchange therapy, known as plasmapheresis. In plasmapheresis, the patient's plasma is replaced with plasma from a healthy donor to treat a variety of medical conditions, including autoimmune diseases and intoxication.

    You may wonder how plasmapheresis works exactly. In this therapy, a specific machine removes blood from the body, separates plasma from the other blood components, and then smoothly returns the blood cells and platelets back into the body, combining them with the donor's plasma.

    • Autoimmune diseases: This is when the immune system mistakenly attacks healthy body tissues. Examples include Multiple sclerosis, Rheumatoid arthritis, etc. In such cases, plasmapheresis removes the harmful antibodies from the plasma to halt the attack.
    • Intoxication: In cases of severe poisoning, plasmapheresis can be used to extract the toxic substances dissolved in plasma, reducing their effect on the body.

    Furthermore, plasma, rich in clotting factors, is incredibly important in treating haemophilia, a genetic disorder that impairs the body's ability to clot.

    The future of blood plasma in medicine is promising. With ongoing research, more applications and therapeutic uses of blood plasma continue to emerge, proving that the river within our veins holds tremendous potential.

    Blood Serum vs. Plasma: Clearing the Confusion

    Navigating the world of nursing, you often encounter various terms related to blood composition. Two of these terms, blood serum and plasma, may seem interchangeable, yet they have distinct differences. Understanding these differences is crucial in various medical scenarios, particularly in diagnostics and treatment.

    Understanding the Difference: Blood Serum vs Plasma

    In biology, blood is broken down into two main parts: blood cells and plasma. Plasma, as discussed earlier, is the liquid portion of the blood, acting like the highway for the transport of cells, nutrients, and hormones.

    Blood Serum: This is the clear, yellowish part of the blood that remains after the clotting process. It's essentially the same as plasma, minus the clotting factors.

    In other words, when a sample of whole blood clots, the remaining liquid is what we refer to as blood serum. So, while plasma contains fibrinogen (a substance that enables clotting), serum does not because it has been used in forming the clot.

    The Importance of Distinguishing Between Blood Serum and Plasma

    The ability to distinguish between blood plasma and serum is essential, particularly in the medical laboratory setting. The two components are used differently in lab evaluations and tests, impacting diagnosis and treatment.

    Let's take a routine cholesterol check, for instance. In this evaluation, plasma works best because it provides a more comprehensive picture. Plasma contains agents like Low-Density Lipoprotein (LDL) and High-Density Lipoprotein (HDL), which health professionals monitor to assess potential cardiovascular diseases. Serum, on the other hand, may not give such a complete picture since the blood clotting process could potentially reduce the number of these components.

    Furthermore, understanding the difference between serum and plasma is crucial during certain medical treatments. For example, when a patient has experienced excessive blood loss, they will need a blood transfusion. It is necessary to know that plasma should be used in this situation, not serum, due to the clotting factors present in plasma.

    Comparative Study: Blood Serum and Plasma

    In comparing plasma and serum, one key difference stands out — the absence or presence of coagulating factors. See the table below:

    Blood PlasmaBlood Serum
    DefinitionYellowish liquid component of bloodClear liquid left after clotting
    Coagulating FactorsPresentAbsent
    Use in TestsHealth checks, blood disordersIdentifying antibodies

    Being able to distinguish between serum and plasma can help medical professionals ensure accuracy when carrying out blood tests. For example, tests looking for antibodies – like the mononucleosis or HIV test – typically employ serum, because antibodies dwell there after the clotting process, hence are more accurately discerned.

    In conclusion, despite their similarities, blood serum and plasma play different roles in medical processes. Therefore, understanding their functions and components is vital for accurate analysis, diagnosis, and treatment in nursing and other medical practices.

    Plasma Blood - Key takeaways

    • Plasma in blood is the liquid element of the blood that holds the blood cells in suspension and forms about 55% of the body's total blood volume.
    • Components of blood plasma include water, proteins, salts, hormones, glucose, and clotting factors which all perform unique functions in the human body.
    • Functions of plasma in blood are vast, including transportation of substances, prevention of excessive bleeding, maintaining the body's pH balance, defending against diseases, and regulating body temperature.
    • Blood plasma has important roles in healthcare and medical therapy, serving as a vital element in plasmapheresis and in the treatment of haemophilia.
    • Blood serum and plasma, although similar, have distinct differences that are important in medical scenarios. The primary difference is that plasma contains coagulating factors while serum does not as it is what remains after the clotting process.
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    Frequently Asked Questions about Plasma Blood
    What is the role of a nurse in plasma blood transfusions?
    A nurse's role in plasma blood transfusions includes assessing the patient's condition, monitoring for reactions during the transfusion, administering the plasma, and documenting the procedure. They also provide education to patients about the process and potential side effects.
    How does a nurse prepare a patient for a plasma blood transfusion?
    A nurse prepares a patient for a plasma blood transfusion by explaining the procedure, obtaining informed consent, checking the patient's vital signs, confirming the patient's blood type, and setting up the transfusion equipment. The nurse also ensures that the patient is comfortable and addresses any concerns.
    What precautions should nurses take when handling plasma blood?
    Nurses handling plasma blood should adhere to standard precautions such as wearing personal protective equipment (PPE), including gloves, gowns, and eye protection. They should follow safe handling and disposal of sharps, practice proper hand hygiene, and ensure the clean-up of any spills immediately.
    What are the potential risks a nurse should consider during a plasma blood transfusion?
    The potential risks a nurse should consider during a plasma blood transfusion include allergic reactions, transfusion reactions (such as fever, chills, and low back pain), transfusion-related acute lung injury, circulatory overload, and disease transmission (including HIV and hepatitis).
    How is plasma blood stored and managed by nurses in a healthcare setting?
    In a healthcare setting, nurses store plasma blood in specialised refrigeration units at temperatures between -25 to -40 degrees Celsius. Management involves regularly checking storage conditions, recording inventory and ensuring safe and hygienic handling following specific protocols.
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